Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827392 | 0.82 | HDAC1 (0.38) | MAPTSMN1; SMN2KDM4ETDP1HDAC1 | |
| SCHEMBL317823 | 0.78 | MTNR1A (0.47) | ASF1AALDH1A1 | |
| SCHEMBL14837249 | 0.76 | KDM1A (0.39) | ASF1A | |
| SCHEMBL8478752 | 0.74 | ASF1A (0.38) | ASF1AGRIK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13681453 | 0.73 | POLB (0.45) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL18660610 | 0.73 | MAPT (0.36) | MAPTSMN1; SMN2KDM4ETDP1ALDH1A1 | |
| SCHEMBL13503753 | 0.72 | ESRRG (0.39) | MAPTMAOB | |
| SCHEMBL13503866 | 0.72 | SIGMAR1 (0.41) | ALDH1A1KMT2ALMNA | |
| SCHEMBL891343 | 0.72 | ALDH1A1 (0.41) | ASF1AGRIK1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2432464 | 0.72 | ALDH1A1 (0.41) | ASF1AGRIK1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006022731-A1 | REUSABLE FRIEDEL-CRAFTS CATALYSTS, THEIR USE, AND THEIR REGENERATION | ALBEMARLE CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |