Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424592 | 0.82 | TSHR (0.46) | ALOX5LMNATSHRMAPTMEN1 | |
| SCHEMBL6170807 | 0.80 | LMNA (0.50) | EGFRLMNATSHRMAPTMEN1 | |
| SCHEMBL9898507 | 0.77 | NR4A2 (0.50) | EGFRLMNATSHRMAPTMEN1 | |
| SCHEMBL1959313 | 0.76 | LMNA (0.46) | ALOX5LMNATSHRMAPTMEN1 | |
| SCHEMBL25143785 | 0.76 | SLC6A3 (0.54) | LMNATSHRMAPTMEN1KMT2A | |
| SCHEMBL1791233 | 0.76 | KDM4E (0.66) | ALOX5LMNATSHRMAPTMEN1 | |
| SCHEMBL27875963 | 0.74 | HTT (0.50) | LMNATSHRMAPTMEN1KMT2A | |
| SCHEMBL2470133 | 0.74 | LMNA (0.55) | EGFRNOX4ALOX5LMNATSHR | |
| SCHEMBL8409708 | 0.74 | LMNA (0.50) | LMNATSHRMAPTMEN1KMT2A | |
| SCHEMBL28283410 | 0.73 | LMNA (0.53) | EGFRNOX4ALOX5LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7976739-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100230649-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230649-A1 | CHROMENE COMPOUND | CCNT1, RB1, H1-0 | EGFR 2387/4885NOX4 498/4885ALOX5 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.