SCHEMBL12424682

SCHEMBL12424682

CN(c1ccccc1)c1cccc(NOO)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.41
MTNR1B P49286 6/20 0.41
ALDH1A1 P00352 2/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
NR3C2 P08235 1/20 0.40
GAA P10253 1/20 0.38
ALOX15 P16050 1/20 0.38
KDM1A O60341 1/20 0.38
CHKA P35790 1/20 0.37
NR3C1 P04150 1/20 0.37
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDK2 Q15119 1/20 0.36
FGFR1 P11362 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424703 0.86 MTNR1A (0.40) MTNR1AMTNR1BALDH1A1BCHEACHE
SCHEMBL12424686 0.81 SIGMAR1 (0.49) ALDH1A1GAAKDM1ARAB9A
SCHEMBL11809039 0.75 MTNR1A (0.61) MTNR1AMTNR1BALDH1A1NPC1HTT
SCHEMBL12258323 0.74 CHKA (0.50) MTNR1AMTNR1BALDH1A1NR3C2GAA
SCHEMBL574779 0.72
SCHEMBL9481726 0.71 NR3C2 (0.78) ALDH1A1NR3C2ALOX15NR3C1TP53
SCHEMBL11558434 0.71 HTT (0.47) ALDH1A1GAAALOX15CHKANR3C1
Diphenylamine SCHEMBL2721122 0.71 HSD17B10 (0.60) ALDH1A1NR3C2ALOX15CHKAHTT
SCHEMBL27520964 0.70 L3MBTL1 (0.59) ALDH1A1GAAALOX15TP53HTT
Hydrochloric Acid SCHEMBL7805041 0.70 IDO1 (0.46) ALDH1A1GAAALOX15NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028977-B2 Compound, method for preparing same and organic electronic device using same LG CHEM, LTD. (KR) 2015-05-12 US disclosed
US-20110168992-A1 NOVEL COMPOUND, METHOD FOR PREPARING SAME AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110168992-A1 NOVEL COMPOUND, METHOD FOR PREPARING SAME AND ORGANIC ELECTRONIC DEVICE USING SAME OR10J3, USE1, NOTUM MTNR1A 4671/4885MTNR1B 4497/4885ALDH1A1 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.