SCHEMBL12424754

SCHEMBL12424754

CCOc1ccc(C2=C3C(=O)NC(c4ccc(OCC)cc4)=C3C(=O)N2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.50
ALDH1A1 P00352 5/20 0.46
PIM1 P11309 1/20 0.46
PIM2 Q9P1W9 1/20 0.46
TP53 P04637 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
MGAT2 Q10469 1/20 0.42
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 2/20 0.41
XDH P47989 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41
MPI P34949 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPT P10636 4/20 0.41
GUSB P08236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23424163 0.92 LTA4H (0.53) NQO1ALDH1A1PIM1PIM2KDM4E
SCHEMBL25636560 0.83 RARB (0.50) TP53TSHRLMNA
SCHEMBL17085502 0.82 RARB (0.52) TP53TSHRLMNA
SCHEMBL19011934 0.81 FFAR1 (0.44) TP53RAB9ASMN1; SMN2XDHGAA
SCHEMBL7004111 0.79 PTGS2 (0.54) TDP1KDM4EMAPTLMNACA12
SCHEMBL3673533 0.79 NQO1 (0.47) NQO1ALDH1A1PIM1PIM2TP53
SCHEMBL12424895 0.79 MAPT (0.48) TP53TDP1SMN1; SMN2HSD17B10KDM4E
SCHEMBL13204622 0.78 RARB (0.48) TP53TSHRMGAT2LMNA
SCHEMBL13204639 0.77 PTGES (0.49) TP53TSHRRAB9ASMN1; SMN2HSD17B10
SCHEMBL18029835 0.77 NR5A1 (0.63) ALDH1A1TP53TSHRRAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657182-B2 Curable resin composition, production method of image sensor chip using the same, and image sensor chip FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed