SCHEMBL12424895

SCHEMBL12424895

CCOc1cccc(C2=C3C(=O)NC(c4ccc(F)cc4)=C3C(=O)N2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
THRB P10828 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NR3C1 P04150 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
GSK3B P49841 2/20 0.44
GSK3A P49840 1/20 0.44
FGFR2 P21802 2/20 0.41
FGFR3 P22607 2/20 0.41
FGFR1 P11362 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 2/20 0.41
PTGS2 P35354 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424754 0.79 NQO1 (0.50) MAPTGAAKDM4ETDP1SMN1; SMN2
SCHEMBL12424960 0.78 SLC5A1 (0.38) GSK3BPRKCASTK10SLK
SCHEMBL8502944 0.75 PTGS1 (0.46) MAPTKDM4ETHRBGSK3BTP53
SCHEMBL12424865 0.75 MAPT (0.41) MAPTTDP1MEN1KMT2AHSD17B10
SCHEMBL5892139 0.74 GAA (0.53) GAAGSK3BPRKCABRD4NOTUM
SCHEMBL12424857 0.73 LMNA (0.44) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL12425000 0.73 TP53 (0.45) MAPTNR3C1RXRATP53NOTUM
SCHEMBL23424163 0.72 LTA4H (0.53) MAPTKDM4EPTGS2
SCHEMBL12424864 0.72 NOTUM (0.44) THRBMEN1KMT2ANOTUMSTK10
SCHEMBL25026520 0.71 ACHE (0.48) MAPTKDM4ESMN1; SMN2PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed