SCHEMBL12424960

SCHEMBL12424960

CCCc1cccc(C2=C3C(=O)NC(c4ccc(F)cc4)=C3C(=O)N2)c1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 4/20 0.38
AGXT P21549 1/20 0.38
STK10 O94804 1/20 0.36
SLK Q9H2G2 1/20 0.36
PRKCA P17252 1/20 0.35
GSK3B P49841 1/20 0.35
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22193360 0.79 PPARG (0.43)
SCHEMBL18015823 0.78 AGXT (0.57) AGXTCTSSCTSK
SCHEMBL12424895 0.78 MAPT (0.48) STK10SLKPRKCAGSK3B
SCHEMBL12424857 0.77 LMNA (0.44)
SCHEMBL8502944 0.76 PTGS1 (0.46) STK10SLKGSK3B
SCHEMBL12424865 0.76 MAPT (0.41) PRKCA
SCHEMBL12425000 0.74 TP53 (0.45) STK10SLK
SCHEMBL12424864 0.73 NOTUM (0.44) STK10SLK
SCHEMBL13579026 0.73 LOXL2 (0.45) PRKCA
SCHEMBL24942184 0.72 AOC3 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed