SCHEMBL12424865

SCHEMBL12424865

O=C1NC(c2ccc(F)cc2)=C2C(=O)NC(c3ccc(F)cc3)=C12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.40
METAP1 P53582 2/20 0.38
ERCC1 P07992 2/20 0.37
ERCC4 Q92889 2/20 0.37
NOTUM Q6P988 1/20 0.37
MAPK14 Q16539 1/20 0.37
PIM1 P11309 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
MEN1 O00255 1/20 0.36
PRKD3 O94806 1/20 0.36
EGFR P00533 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
SRC P12931 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36
PRKCE Q02156 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8502944 0.92 PTGS1 (0.46) MAPTMAPK14MEN1KMT2APTGS1
SCHEMBL25026520 0.90 ACHE (0.48) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL12424998 0.89 MAPT (0.34) MAPTPOLBMETAP1ERCC1ERCC4
SCHEMBL12424997 0.87 NPY5R (0.42) NOTUMPIM1PIM2PTGS1
SCHEMBL12424993 0.87 MAPT (0.37) MAPTPOLBMETAP1ERCC1ERCC4
SCHEMBL12424857 0.86 LMNA (0.44) MAPTNOTUMMAPK14PIM1PIM2
SCHEMBL12509874 0.84 RORC (0.40) MAPTPOLBMETAP1
SCHEMBL12424982 0.83 RXRA (0.38) MAPTKMT2AALDH1A1HTT
SCHEMBL12425000 0.79 TP53 (0.45) MAPTNOTUM
SCHEMBL12424968 0.79 TGM2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed