SCHEMBL12424930

SCHEMBL12424930

O=C1NC(c2cccc(C(F)(F)F)c2F)=C2C(=O)NC(c3cccc(C(F)(F)F)c3F)=C12

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.50
STK10 O94804 9/20 0.46
SLK Q9H2G2 9/20 0.46
MPL P40238 3/20 0.41
HCAR1 Q9BXC0 1/20 0.36
NOTUM Q6P988 3/20 0.36
KDM1A O60341 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424926 0.89 CES1 (0.41) CES1STK10SLKMPL
SCHEMBL12424904 0.84 STK10 (0.51) CES1STK10SLKNOTUM
SCHEMBL12424870 0.79 CA1 (0.38) CES1STK10SLK
SCHEMBL12425006 0.77 STK10 (0.56) CES1STK10SLK
SCHEMBL12424933 0.77 STK10 (0.46) CES1STK10SLK
SCHEMBL12424890 0.76 CES1 (0.44) CES1STK10SLK
SCHEMBL12425008 0.73 STK10 (0.44) CES1STK10SLK
SCHEMBL12424862 0.71 GSK3B (0.44) NOTUM
SCHEMBL12425005 0.70 JAK3 (0.53) CES1STK10SLK
SCHEMBL12424892 0.69 GRM5 (0.35) CES1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed