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SCHEMBL12424926

SCHEMBL12424926

O=C1NC(c2cccc(C(F)(F)F)c2F)=C2C(=O)NC(c3ccc(C(F)(F)F)cc3)=C12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 1/20 0.41
▸ STK10 O94804 9/20 0.39
▸ SLK Q9H2G2 9/20 0.39
▸ TDP2 O95551 1/20 0.36
▸ PARP1 P09874 2/20 0.36
▸ KDR P35968 1/20 0.36
▸ PARP2 Q9UGN5 1/20 0.35
▸ MPL P40238 2/20 0.35
▸ TRPV1 Q8NER1 2/20 0.33
▸ MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424930 0.89 CES1 (0.50) CES1STK10SLKMPL
SCHEMBL12424740 0.81 TDP2 (0.45) CES1TDP2
SCHEMBL12424858 0.78 KIF11 (0.57) TDP2PARP1PARP2TRPV1
SCHEMBL12424997 0.78 NPY5R (0.42) TDP2PARP1
SCHEMBL12424986 0.77 TDP2 (0.38) TDP2
SCHEMBL12424979 0.76 PARP10 (0.46) STK10SLKTDP2
SCHEMBL12424987 0.76 TDP2 (0.40) TDP2
SCHEMBL12424904 0.75 STK10 (0.51) CES1STK10SLK
SCHEMBL12424995 0.74 TDP2 (0.43) TDP2
SCHEMBL12425041 0.74 PTGS2 (0.41) TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 — — US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 — — US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 — — US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 — — US disclosed