Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24248786 | 0.84 | SELL (0.48) | SELLSELPSELEMEN1LMNA | |
| SCHEMBL776662 | 0.80 | RAPGEF4 (0.33) | RAPGEF4ALDH1A1 | |
| SCHEMBL12410554 | 0.78 | — | — | |
| SCHEMBL11944942 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL3112802 | 0.76 | DGAT1 (0.30) | — | |
| SCHEMBL13087969 | 0.76 | — | — | |
| SCHEMBL15109864 | 0.76 | TAAR1 (0.39) | MEN1LMNATP53GAAMAPT | |
| SCHEMBL19574353 | 0.74 | HDAC1 (0.34) | SELLSELPSELERAPGEF4NFE2L2 | |
| SCHEMBL12390578 | 0.72 | GABRA1 (0.37) | MEN1GAAMAPTHPGDALOX15 | |
| SCHEMBL30748398 | 0.72 | TAAR1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013062837-A1 | PIPERIDINE DERIVATIVES USEFUL AS GPR119 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2011103509-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | ACEA BIOSCIENCES INC. (US) | 2011-08-25 | — | — | WO | disclosed |