Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695667 | 1.00 | THRB (0.46) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL12386523 | 0.86 | THRB (0.44) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6686136 | 0.84 | HTR2A (0.50) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6686484 | 0.84 | HTR2A (0.40) | AOC3KDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL6692689 | 0.82 | ALDH1A1 (0.53) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL12319469 | 0.82 | ALDH1A1 (0.53) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6689517 | 0.79 | THRB (0.47) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL13802349 | 0.75 | THRB (0.35) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL13802352 | 0.75 | THRB (0.35) | THRBAOC3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL5474344 | 0.75 | THRB (0.57) | THRBALDH1A1CYP3A4HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994355-B2 | Metallocene-based chiral phosphine or arsine ligands | SOLVIAS AG (CH) | 2011-08-09 | — | — | US | disclosed |
| EP-1709054-B1 | METALLOCENE-BASED CHIRAL PHOSPHINE OR ARSINE LIGANDS | PHOENIX CHEMICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-20070161762-A1 | Metallocene-based chiral phosphine or arsine ligands | PHOENIX CHEMICALS LIMITED (GB) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161762-A1 | Metallocene-based chiral phosphine or arsine ligands | OSGEP, PHOSPHO1, ITPA | THRB 2928/4885AOC3 1457/4885KDM4E 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.