Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721382 | 0.87 | KDM4E (0.48) | HTR2AHRH1LMNACYP1A2CHRM2 | |
| SCHEMBL12426593 | 0.84 | THRB (0.46) | HTR2AHRH1LMNACYP1A2CHRM2 | |
| SCHEMBL6695667 | 0.84 | THRB (0.46) | HTR2AHRH1LMNACYP1A2CHRM2 | |
| SCHEMBL9750485 | 0.79 | TAAR1 (0.42) | HTR2AHRH1LMNACYP1A2CHRM2 | |
| SCHEMBL6558951 | 0.76 | LMNA (0.47) | HTR2ALMNACHRM2ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL22774123 | 0.74 | ALDH1A1 (0.47) | LMNAADRA2ACYP2D6HTTKDM4E | |
| Hydrochloric Acid SCHEMBL22775398 | 0.74 | ALDH1A1 (0.47) | LMNAADRA2ACYP2D6HTTKDM4E | |
| SCHEMBL19312229 | 0.73 | LMNA (0.48) | LMNAADRA2ATSHRKDM4EALDH1A1 | |
| SCHEMBL23804980 | 0.73 | L3MBTL1 (0.41) | LMNACYP1A2HTTKDM4EALDH1A1 | |
| SCHEMBL5867158 | 0.73 | HTR2A (0.48) | HTR2AHRH1LMNACYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990670-B1 | Calcium-based catalyst system | GOODYEAR TIRE & RUBBER (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2004082565-A2 | ASYMMETRIC CYCLIZATION IN THE PRESENCE OF SUBSTITUTED PSEUDOPHEDRINES | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |