Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426929 | 1.00 | TDP1 (0.43) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL2198911 | 0.96 | TDP1 (0.46) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL2198915 | 0.77 | MAPT (0.43) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL5321709 | 0.72 | TDP1 (0.57) | TDP1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12426928 | 0.71 | EPHX1 (0.37) | MEN1KMT2A | |
| SCHEMBL12426942 | 0.71 | EPHX1 (0.37) | MEN1KMT2A | |
| SCHEMBL12426955 | 0.71 | NPC1 (0.40) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5321454 | 0.71 | MAPT (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29900467 | 0.71 | KDM4E (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11710551 | 0.71 | KDM4E (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |