Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198911 | 0.81 | TDP1 (0.46) | MAPTALDH1A1TDP1HSD17B3KDM4E | |
| SCHEMBL12426929 | 0.77 | TDP1 (0.43) | MAPTALDH1A1TDP1HSD17B3KDM4E | |
| SCHEMBL12426934 | 0.77 | TDP1 (0.43) | MAPTALDH1A1TDP1HSD17B3KDM4E | |
| SCHEMBL11710551 | 0.70 | KDM4E (0.57) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL29900467 | 0.70 | KDM4E (0.57) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL5656392 | 0.69 | ALDH1A1 (0.57) | MAPTALDH1A1TDP1HSD17B3KDM4E | |
| SCHEMBL5655669 | 0.67 | KDM4E (0.65) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL964439 | 0.66 | KDM4E (0.58) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL14328044 | 0.65 | ALDH1A1 (0.43) | MAPTALDH1A1KMT2ALMNAHTT | |
| SCHEMBL5321709 | 0.64 | TDP1 (0.57) | MAPTALDH1A1TDP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20080262238-A1 | Dendron and Dendrimer, Method of Producing the Same, and Method of Producing a Thioacetal Compound | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1730106-A4 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJIFILM CORP (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1730106-A1 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092847-A1 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262238-A1 | Dendron and Dendrimer, Method of Producing the Same, and Method of Producing a Thioacetal Compound | TXN, TST, TTL | MAPT 439/4885ALDH1A1 162/4885TDP1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.