Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426929 | 0.96 | TDP1 (0.43) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL12426934 | 0.96 | TDP1 (0.43) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL2198915 | 0.81 | MAPT (0.43) | TDP1MAPTALDH1A1LMNARECQL | |
| SCHEMBL5321709 | 0.75 | TDP1 (0.57) | TDP1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5321454 | 0.74 | MAPT (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29900467 | 0.74 | KDM4E (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11710551 | 0.74 | KDM4E (0.57) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27450371 | 0.73 | MAPT (0.54) | MAPTALDH1A1LMNACSNK2A2CSNK2B | |
| SCHEMBL2204262 | 0.72 | TDP1 (0.54) | TDP1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5320690 | 0.71 | MAPT (0.60) | TDP1MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20080262238-A1 | Dendron and Dendrimer, Method of Producing the Same, and Method of Producing a Thioacetal Compound | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1730106-A4 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJIFILM CORP (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1730106-A1 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092847-A1 | DENDRON AND DENDRIMER, METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING A THIOACETAL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262238-A1 | Dendron and Dendrimer, Method of Producing the Same, and Method of Producing a Thioacetal Compound | TXN, TST, TTL | TDP1 1614/4885MAPT 439/4885ALDH1A1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.