Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427065 | 0.83 | HPGD (0.49) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12427062 | 0.83 | SQOR (0.53) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL17450996 | 0.82 | RAB9A (0.48) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14943936 | 0.78 | HPGD (0.43) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2300943 | 0.77 | ALDH1A1 (0.50) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3208786 | 0.76 | L3MBTL1 (0.43) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14931843 | 0.76 | HPGD (0.41) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL25047250 | 0.75 | SQOR (0.59) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27518492 | 0.74 | SQOR (0.53) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13831044 | 0.74 | MEN1 (0.54) | HPGDRAB9ANPC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | GENFIT (FR) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | PPARD, PPARA, PPARG | HPGD 1128/4885RAB9A 2825/4885NPC1 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.