SCHEMBL12428201

SCHEMBL12428201

Cc1ccc(N2CCCc3cc(/C=C4\C(=O)N(c5ccc6ccccc6c5)N=C4C(=O)O)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 1/20 0.41
KMT2A Q03164 7/20 0.39
MEN1 O00255 6/20 0.39
TDP2 O95551 1/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
BCL2 P10415 1/20 0.38
BAX Q07812 1/20 0.38
BCL2L1 Q07817 1/20 0.38
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
POLB P06746 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428142 0.93 TDP2 (0.40) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428121 0.93 KAT8 (0.45) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428192 0.92 KAT8 (0.43) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428202 0.91 KAT8 (0.43) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428185 0.90 TDP2 (0.41) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428200 0.89 KMT2A (0.39) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428170 0.88 KMT2A (0.44) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428181 0.86 KMT2A (0.49) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL12428117 0.86 ALDH1A1 (0.44) KAT8KMT2AMEN1TDP2ALDH1A1
SCHEMBL14289377 0.86 KMT2A (0.42) KAT8KMT2AMEN1TDP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 KAT8 1908/4885KMT2A 105/4885MEN1 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.