Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12428255 | 0.89 | PRKCA (0.40) | PRKCAMMP12ROCK2VDRNR1H4 | |
| SCHEMBL12428350 | 0.89 | PRKCA (0.46) | PRKCAMMP12ROCK2VDRNR1H4 | |
| SCHEMBL772271 | 0.81 | PRKCA (0.47) | PRKCAMMP12ROCK2VDRNR1H4 | |
| SCHEMBL12429245 | 0.80 | PRKCA (0.45) | PRKCAMMP12VDRNR1H4 | |
| SCHEMBL12429409 | 0.78 | PRKCA (0.46) | PRKCAMMP12VDRNR1H4GLP1R | |
| SCHEMBL12429233 | 0.78 | PRKCA (0.48) | PRKCAMMP12KCNH2SCN9ANR1I2 | |
| SCHEMBL804548 | 0.77 | L3MBTL1 (0.42) | PRKCAMMP12SCN9AALOX5APFEN1 | |
| SCHEMBL12427922 | 0.77 | PRKCA (0.51) | PRKCAMMP12NR1I2 | |
| SCHEMBL792699 | 0.77 | PRKCA (0.41) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL12429287 | 0.77 | PRKCA (0.46) | PRKCAMMP12KCNH2SCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |