Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL771502 | 0.99 | ADAM17 (0.30) | PIK3CAADAM17PDE7A | |
| SCHEMBL12428670 | 0.92 | FFAR4 (0.34) | PIK3CAADAM17 | |
| Hydrochloric Acid SCHEMBL772629 | 0.91 | FFAR4 (0.34) | PIK3CA | |
| SCHEMBL10283203 | 0.89 | PRKCA (0.38) | — | |
| Hydrochloric Acid SCHEMBL772348 | 0.88 | PRKCA (0.38) | — | |
| SCHEMBL13476323 | 0.84 | — | — | |
| SCHEMBL12428671 | 0.82 | TRPM8 (0.34) | — | |
| Hydrochloric Acid SCHEMBL771301 | 0.82 | TRPM8 (0.34) | — | |
| SCHEMBL3785533 | 0.81 | PRKCA (0.39) | — | |
| SCHEMBL804172 | 0.80 | PRKCA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |