SCHEMBL12430010

SCHEMBL12430010

COCCC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.38
STING1 Q86WV6 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 3/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA14 Q9ULX7 1/20 0.35
EPHX2 P34913 1/20 0.33
CYP2D6 P10635 1/20 0.33
MLYCD O95822 1/20 0.33
MTNR1A P48039 4/20 0.33
MTNR1B P49286 4/20 0.33
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12914653 0.92 ADRA2A (0.38) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL916562 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL21877221 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL1781057 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL19532914 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL24668232 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL917272 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL917567 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL12592808 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1
SCHEMBL29467625 0.87 STING1 (0.37) DGAT1STING1ALDH1A1TSHRHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376094-A2 SELECTIVE BCL-XL PROTAC COMPOUNDS AND METHODS OF USE LES LABORATOIRES SERVIER (FR) 2024-11-14 US disclosed
US-20240226320-A1 DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES SEAGEN INC (US) 2024-07-11 US disclosed
EP-4288434-A1 SELECTIVE BCL-XL PROTAC COMPOUNDS AND METHODS OF USE Les Laboratoires Servier (FR) 2023-12-13 EP disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 US disclosed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
US-10808048-B2 Process of manufacture of catalyst and propylene polymer that use this or copolymer for propylene polymerization HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2020-10-20 US disclosed
EP-3683243-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2020-07-22 EP disclosed
US-10029993-B2 Disubstituted 1, 2, 4-triazine compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2018-07-24 US disclosed
US-20180155461-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-07 US disclosed
EP-3330299-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2018-06-06 EP disclosed
US-7255971-B2 Positive resist composition FUJIFILM CORPORATION (JP) 2007-08-14 US disclosed
US-7252924-B2 Positive resist composition and method of pattern formation using the same FUJIFILM CORPORATION (JP) 2007-08-07 US disclosed
US-7241551-B2 Positive-working resist composition FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
US-7235341-B2 Positive resist composition FUJIFILM CORPORATION (JP) 2007-06-26 US disclosed
US-20070141513-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-06-21 US disclosed
US-7214465-B2 Positive photosensitive composition FUJIFILM CORPORATION (JP) 2007-05-08 US disclosed
US-7214733-B2 Positive type resist composition FUJI PHOTO FILM CO., LTD. (JP) 2007-05-08 US disclosed
US-7195856-B2 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-03-27 US disclosed
US-7192681-B2 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
US-7179578-B2 Positive resist composition FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226320-A1 DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES CD44, CD47, UACA DGAT1 3353/4885STING1 4580/4885ALDH1A1 553/4885
US-20240376094-A2 SELECTIVE BCL-XL PROTAC COMPOUNDS AND METHODS OF USE CRBN, XIAP, BCL2L11 DGAT1 3558/4885STING1 4384/4885ALDH1A1 3085/4885
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS SREBF1, SREBF2, NR1H3 DGAT1 154/4885STING1 2061/4885ALDH1A1 3647/4885
US-10029993-B2 Disubstituted 1, 2, 4-triazine compound NR3C2, REN, NR5A1 DGAT1 2075/4885STING1 4657/4885ALDH1A1 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.