Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893494 | 0.90 | TTBK1 (0.45) | TTBK1TTBK2LMNAHPGDPOLB | |
| SCHEMBL9258744 | 0.83 | KDM4E (0.45) | TTBK1TTBK2LMNAHPGDPOLB | |
| SCHEMBL3657085 | 0.81 | KDM4E (0.46) | TTBK1TTBK2LMNAHPGDPOLB | |
| SCHEMBL507057 | 0.74 | TTBK1 (0.47) | TTBK1TTBK2LMNAHPGDPOLB | |
| SCHEMBL25891383 | 0.74 | IDH1 (0.41) | LMNAPOLBMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL23891754 | 0.73 | MTNR1A (0.48) | ALDH1A1MGAMAMY1AGAASI | |
| SCHEMBL9222529 | 0.73 | SMN1; SMN2 (0.53) | LMNAHPGDPOLBMAPK1KDM4E | |
| SCHEMBL11754066 | 0.72 | ALDH1A1 (0.53) | TTBK1TTBK2LMNAHPGDPOLB | |
| SCHEMBL309485 | 0.71 | TLR8 (0.53) | POLBKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9440359 | 0.71 | MTNR1A (0.48) | MTNR1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192622-A1 | ANTI-SARS-COV-2 DRUG | ONCOLYS BIOPHARMA, INC. (JP) | 2023-06-22 | — | — | US | disclosed |
| EP-2532652-B1 | THERAPEUTIC AGENT FOR HEPATITIS C | UNIV KAGOSHIMA (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-20120316342-A1 | THERAPEUTIC AGENT FOR HEPATITIS C | ONCOLYS BIOPHARMA, INC. (JP) | 2012-12-13 | — | — | US | disclosed |
| US-20120316342-A1 | THERAPEUTIC AGENT FOR HEPATITIS C | ONCOLYS BIOPHARMA, INC. (JP) | 2012-12-13 | — | — | US | disclosed |
| EP-2532652-A1 | THERAPEUTIC AGENT FOR HEPATITIS C | Kagoshima University (JP) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011093483-A1 | THERAPEUTIC AGENT FOR HEPATITIS C | 国立大学法人鹿児島大学 (JP) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192622-A1 | ANTI-SARS-COV-2 DRUG | ACE2, ACE, SARS1 | TTBK1 4369/4885TTBK2 3336/4885LMNA 2524/4885 |
| US-20120316342-A1 | THERAPEUTIC AGENT FOR HEPATITIS C | HAVCR2, SLC10A1, FABP1 | TTBK1 2969/4885TTBK2 3588/4885LMNA 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.