Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207267 | 0.85 | MTNR1A (0.47) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL2206369 | 0.85 | MTNR1A (0.47) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL14784609 | 0.84 | MTNR1A (0.47) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL14044242 | 0.79 | CA12 (0.43) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL6068723 | 0.79 | MTNR1A (0.44) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL6068727 | 0.79 | MTNR1A (0.44) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL10509506 | 0.79 | MTNR1A (0.46) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL12944996 | 0.78 | SCN5A (0.39) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL4797235 | 0.78 | MTNR1A (0.43) | SCN5AMTNR1AMTNR1BKMT2ACA12 | |
| SCHEMBL29588480 | 0.78 | MTNR1A (0.43) | SCN5AMTNR1AMTNR1BKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7982054-B2 | Process for the synthesis of N-[3-[(2-methoxyphenyl] sulfanyl] -2-methylpropyl] -3,4-dihydro-2H-1,5-benzoxathiepin-3-amine | PIERRE FABRE MEDICAMENT (FR) | 2011-07-19 | — | — | US | disclosed |
| US-20090318709-A1 | PROCESS FOR THE SYNTHESIS OF N-[3-[(2-METHOXYPHENYL] SULFANYL] -2-METHYLPROPYL] -3,4-DIHYDRO-2H-1,5-BENZOXATHIEPIN-3-AMINE. | PIERRE FABRE MEDICAMENT (FR) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318709-A1 | PROCESS FOR THE SYNTHESIS OF N-[3-[(2-METHOXYPHENYL] SULFANYL] -2-METHYLPROPYL] -3,4-DIHYDRO-2H-1,5-BENZOXATHIEPIN-3-AMINE. | HTR3A, DHPS, HTR3C | SCN5A 586/4885MTNR1A 1095/4885MTNR1B 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.