Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433898 | 0.97 | SIGMAR1 (0.35) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL17264027 | 0.91 | SIGMAR1 (0.32) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL14297989 | 0.85 | CCR1 (0.38) | TDP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL23764165 | 0.84 | MAPT (0.38) | ALDH1A1HPGDHSD17B10TSHRL3MBTL1 | |
| SCHEMBL12433944 | 0.84 | HSD17B1 (0.35) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL12433938 | 0.84 | HSD17B1 (0.35) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL12728721 | 0.83 | PDK2 (0.33) | LMNA | |
| SCHEMBL25793181 | 0.83 | ALDH1A1 (0.33) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL10029021 | 0.82 | ALDH1A1 (0.41) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL10025665 | 0.82 | ALDH1A1 (0.42) | TDP1ALDH1A1HPGDCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981523-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981523-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |