SCHEMBL23764165

SCHEMBL23764165

Cc1cccc(N(c2ccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)cc2)c2cccc(C)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 3/20 0.38
PABPC1 P11940 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KEAP1 Q14145 3/20 0.37
NFE2L2 Q16236 3/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HPGD P15428 2/20 0.36
CASP1 P29466 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
HTT P42858 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20016861 0.89 MAPT (0.36) MAPTKDM4EPABPC1SMN1; SMN2KEAP1
SCHEMBL23764074 0.87 HTT (0.33) MAPTKDM4EKEAP1NFE2L2ALDH1A1
SCHEMBL401883 0.87 HSD17B1 (0.38) MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL9888927 0.86 CRHBP (0.44) MAPTKDM4EPABPC1SMN1; SMN2KEAP1
SCHEMBL14010643 0.86 MEN1 (0.37) MAPTKDM4EPABPC1SMN1; SMN2KEAP1
SCHEMBL12914342 0.84 CA12 (0.43) HSD17B1HSD17B2SIGMAR1ENPP3ENPP1
SCHEMBL12433898 0.84 SIGMAR1 (0.35) MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL23764168 0.84 KDM4E (0.37) MAPTKDM4EPABPC1SMN1; SMN2KEAP1
SCHEMBL12433899 0.84 TDP1 (0.35) MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL23764501 0.84 KDM4E (0.38) MAPTKDM4EPABPC1SMN1; SMN2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed