Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504617 | 0.90 | SMN1; SMN2 (0.56) | GAALMNAKDM4ESMN1; SMN2TSHR | |
| SCHEMBL23699040 | 0.85 | GAA (0.62) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL12330918 | 0.85 | GAA (0.67) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL3903156 | 0.85 | GAA (0.76) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL9779397 | 0.84 | GAA (0.60) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL23707785 | 0.82 | SMN1; SMN2 (0.57) | GAALMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL29497614 | 0.82 | GAA (1.00) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL18628071 | 0.82 | GAA (0.62) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL8433585 | 0.82 | ALDH1A1 (0.66) | GAALMNAKDM4EHPGDDUSP3 | |
| SCHEMBL13655375 | 0.81 | LMNA (0.84) | GAALMNAKDM4EHPGDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858849-A1 | DERIVATIVE BASED ON COMMON ANEMARRHENAE RHIZOME SARSASAPOGENIN STRUCTURE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Phytovent Biopharma (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020062883-A1 | DERIVATIVE BASED ON COMMON ANEMARRHENAE RHIZOME SARSASAPOGENIN STRUCTURE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 深圳清博汇能医药科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
| EP-2351744-A1 | ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE | Shionogi & Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |