Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.84 |
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497614 | 0.90 | GAA (1.00) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL17817601 | 0.89 | LMNA (0.68) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL8587098 | 0.89 | LMNA (0.68) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL2347336 | 0.89 | GAA (0.70) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL30522606 | 0.88 | TDP1 (0.75) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL76649 | 0.87 | GAA (0.68) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL611220 | 0.87 | GAA (0.68) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL8762651 | 0.85 | GAA (0.66) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL11742767 | 0.85 | LMNA (0.69) | LMNAKDM4EGAARAB9APOLB | |
| SCHEMBL2691461 | 0.85 | GAA (0.66) | LMNAKDM4EGAARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468032-B1 | ALKYLAMINO OXAMIDES AS LOW ODOR NON FUGITIVE CATALYSTS FOR THE PRODUCTION OF POLYURETHANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2009-10-21 | — | — | EP | disclosed |