Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488433 | 0.85 | ARG1 (0.56) | GGT1ARG1ARG2BLMGRM4 | |
| SCHEMBL8687592 | 0.80 | GGT1 (0.65) | GGT1ARG1ARG2BLMALDH1A1 | |
| SCHEMBL31688794 | 0.78 | — | — | |
| SCHEMBL5323056 | 0.78 | — | — | |
| SCHEMBL28638811 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27526987 | 0.76 | GGT1 (0.56) | GGT1ARG1ARG2BLMALDH1A1 | |
| SCHEMBL15910255 | 0.76 | ALDH1A1 (0.35) | GGT1GRM4ALDH1A1MEN1KMT2A | |
| SCHEMBL18756508 | 0.76 | ACLY (0.43) | GGT1ALDH1A1CYP1A2KDM4EGAA | |
| SCHEMBL179782 | 0.76 | GRM4 (0.61) | GGT1ARG1ARG2BLMGRM4 | |
| SCHEMBL179781 | 0.76 | GRM4 (0.61) | GGT1ARG1ARG2BLMGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191130-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2017-11-09 | — | — | WO | disclosed |
| WO-2011091548-A1 | METHOD FOR CUCURBITINE SYNTHESIS | UNILEVER PLC (GB) | 2011-08-04 | — | — | WO | disclosed |