Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1580048 | 0.99 | MAPT (0.54) | MAPTSMN1; SMN2GAARAB9AAPLNR | |
| SCHEMBL1579974 | 0.90 | KMT2A (0.53) | MAPTSMN1; SMN2GAARAB9AAPLNR | |
| Hydrochloric Acid SCHEMBL1579944 | 0.89 | LMNA (0.57) | MAPTSMN1; SMN2GAARAB9AAPLNR | |
| SCHEMBL12388558 | 0.87 | MAPT (0.52) | MAPTSMN1; SMN2GAARAB9AAPLNR | |
| SCHEMBL12388570 | 0.83 | MAPK14 (0.51) | MAPTSMN1; SMN2RAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1579990 | 0.82 | MAPK14 (0.50) | MAPTSMN1; SMN2RAB9AKMT2AKDM4E | |
| SCHEMBL7570783 | 0.78 | KMT2A (0.58) | MAPTSMN1; SMN2GAARAB9AKMT2A | |
| SCHEMBL1579925 | 0.78 | KMT2A (0.68) | MAPTSMN1; SMN2GAARAB9AAPLNR | |
| SCHEMBL7132994 | 0.75 | APLNR (0.63) | MAPTSMN1; SMN2RAB9AAPLNRKMT2A | |
| SCHEMBL15693330 | 0.74 | ALDH1A1 (0.62) | MAPTSMN1; SMN2RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190351-A1 | Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2010014794-A1 | BENZOIMIDAZOLE DERIVATIVES AND GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190351-A1 | Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same | GSK3B, GSK3A, GYS2 | MAPT 1213/4885SMN1; SMN2 3707/4885GAA 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.