Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162264 | 0.89 | HPGDS (0.53) | ALDH1A1RAB9AHPGDKDM4EHSD17B10 | |
| SCHEMBL1580091 | 0.84 | ALDH1A1 (0.46) | ALDH1A1RAB9AKDM4EKMT2ANPC1 | |
| SCHEMBL28406827 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL8114736 | 0.81 | ALDH1A1 (0.64) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL2314242 | 0.81 | USP30 (0.54) | ALDH1A1CNR1CNR2 | |
| SCHEMBL11239859 | 0.81 | ALDH1A1 (0.70) | ALDH1A1RAB9AHPGDKDM4EHSD17B10 | |
| SCHEMBL3455875 | 0.81 | ALDH1A1 (0.70) | ALDH1A1RAB9AHPGDKDM4EHSD17B10 | |
| SCHEMBL28684615 | 0.81 | RAB9A (0.61) | ALDH1A1RAB9AHPGDKDM4EHSD17B10 | |
| SCHEMBL12435559 | 0.80 | RAB9A (0.60) | ALDH1A1RAB9AHPGDKDM4EHSD17B10 | |
| SCHEMBL8777820 | 0.80 | ALDH1A1 (0.62) | ALDH1A1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190351-A1 | Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190351-A1 | Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same | GSK3B, GSK3A, GYS2 | ALDH1A1 2860/4885RAB9A 4415/4885HPGD 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.