Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPGS | Q05932 | 2/20 | 0.69 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.68 |
| ▸ | NOS1 | P29475 | 8/20 | 0.60 |
| ▸ | NOS3 | P29474 | 1/20 | 0.60 |
| ▸ | NOS2 | P35228 | 1/20 | 0.60 |
| ▸ | GART | P22102 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922792 | 0.92 | SOST (0.70) | FPGSSOSTNOS1NOS3NOS2 | |
| SCHEMBL30424027 | 0.92 | SOST (0.70) | FPGSSOSTNOS1NOS3NOS2 | |
| SCHEMBL13107427 | 0.83 | SOST (0.71) | FPGSSOSTNOS1NOS3NOS2 | |
| SCHEMBL7100127 | 0.82 | FPGS (1.00) | FPGSSOSTGARTDHFRLMNA | |
| Tetrahydrofolate SCHEMBL8030 | 0.81 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL2691812 | 0.81 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL30051444 | 0.81 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL9879710 | 0.81 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| SCHEMBL12947601 | 0.81 | SOST (0.69) | FPGSSOSTNOS1NOS3NOS2 | |
| Tetrahydrofolate SCHEMBL159231 | 0.81 | SOST (1.00) | FPGSSOSTGARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354142-A1 | Process for the preparation of the amorphous calcium salt of (6S)-N(5)-methyl-5,6,7,8-tetrahydrofolic acid | Cerbios-Pharma S.A. (CH) | 2011-08-10 | — | — | EP | disclosed |