Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060898 | 0.95 | TDP1 (0.67) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL13527201 | 0.93 | TDP1 (0.65) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10042896 | 0.92 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16068455 | 0.89 | CYP2A6 (0.62) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10042908 | 0.87 | CYP19A1 (0.51) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10035345 | 0.85 | HSD11B1 (0.56) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL35988 | 0.84 | CYP2A6 (0.61) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10035337 | 0.83 | HSD11B1 (0.60) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10035324 | 0.83 | HSD11B1 (0.60) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL12303912 | 0.83 | FLT3 (0.52) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-29 | — | — | US | disclosed |
| EP-1802641-B1 | BISPHOSPHONATE COMPOUNDS AND METHODS FOR BONE RESORPTION DISEASES, CANCER, BONE PAIN, IMMUNE DISORDERS, AND INFECTIOUS DISEASES | UNIV ILLINOIS (US) | 2011-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | CYP3A4 2000/4885CYP2D6 151/4885CYP19A1 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.