Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18389961 | 0.88 | MAPT (0.57) | ECE2SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL20037975 | 0.88 | SMN1; SMN2 (0.44) | ECE2SMN1; SMN2POLBNPC1HPGD | |
| SCHEMBL18389949 | 0.85 | HSD11B1 (0.61) | SMN1; SMN2HPGDMEN1KMT2AKDM4E | |
| SCHEMBL18705024 | 0.84 | HRH3 (0.49) | SMN1; SMN2MEN1KMT2AKDM4EPANK3 | |
| SCHEMBL16211006 | 0.81 | KMT2A (0.52) | ECE2SMN1; SMN2NPC1HPGDMEN1 | |
| SCHEMBL14190953 | 0.81 | MEN1 (0.50) | SMN1; SMN2POLBMEN1KMT2AGPR119 | |
| SCHEMBL600778 | 0.78 | ALDH1A1 (0.47) | POLBKMT2AKDM4EHRH3LMNA | |
| SCHEMBL17572094 | 0.78 | MEN1 (0.69) | SMN1; SMN2POLBNPC1HPGDMEN1 | |
| SCHEMBL3613404 | 0.78 | L3MBTL1 (0.56) | ECE2SMN1; SMN2POLBNPC1HPGD | |
| SCHEMBL14084729 | 0.78 | GABRP (0.58) | ECE2SMN1; SMN2POLBNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095997-A1 | BENZAMIDE COMPOUNDS AS GLUCOKINASE ACTIVATORS AND THEIR PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-08-11 | — | — | WO | disclosed |