Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | BCHE | P06276 | 9/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048152 | 0.88 | GGPS1 (0.48) | GGPS1ACHEBCHEFDPSMAPT | |
| SCHEMBL12060366 | 0.87 | GGPS1 (0.52) | GGPS1ACHEBCHEFDPS | |
| SCHEMBL12060353 | 0.70 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048171 | 0.69 | GGPS1 (0.49) | GGPS1FDPS | |
| SCHEMBL14227950 | 0.69 | FDPS (0.37) | GGPS1ACHEFDPS | |
| SCHEMBL5897909 | 0.68 | FDPS (0.71) | GGPS1FDPS | |
| SCHEMBL12060368 | 0.68 | FDPS (0.46) | GGPS1FDPS | |
| SCHEMBL12060370 | 0.68 | GGPS1 (0.47) | GGPS1FDPS | |
| SCHEMBL12048182 | 0.68 | FDPS (0.42) | GGPS1FDPS | |
| SCHEMBL12048185 | 0.68 | GGPS1 (0.57) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802641-B1 | BISPHOSPHONATE COMPOUNDS AND METHODS FOR BONE RESORPTION DISEASES, CANCER, BONE PAIN, IMMUNE DISORDERS, AND INFECTIOUS DISEASES | UNIV ILLINOIS (US) | 2011-08-10 | — | — | EP | disclosed |