Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.71 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.53 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846830 | 0.84 | FDPS (1.00) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL8165606 | 0.82 | FDPS (0.76) | FDPSGGPS1BTN3A1PDE3A | |
| Water SCHEMBL9226518 | 0.76 | FDPS (0.73) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL3419952 | 0.73 | FDPS (0.66) | FDPSGGPS1 | |
| SCHEMBL11044425 | 0.72 | FDPS (0.62) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL7606373 | 0.72 | FDPS (0.70) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL5897462 | 0.70 | PTPN1 (0.47) | FDPSLAP3 | |
| SCHEMBL7605699 | 0.70 | FDPS (0.61) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL7264380 | 0.70 | FDPS (0.67) | FDPSGGPS1LAP3 | |
| SCHEMBL3075655 | 0.70 | FDPS (0.67) | FDPSGGPS1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005533-B2 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS 13 (FR) | 2006-02-28 | — | — | US | disclosed |
| US-20040266735-A1 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS 13 | 2004-12-30 | — | — | US | disclosed |
| US-20030036537-A1 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS, 13 (FR) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036537-A1 | Bisphosphonate derivatives, their preparations and uses | BPGM, PPIP5K2, PTEN | FDPS 36/4885GGPS1 21/4885BTN3A1 1809/4885 |
| US-20040266735-A1 | Bisphosphonate derivatives, their preparations and uses | BPGM, PPIP5K2, PTEN | FDPS 36/4885GGPS1 21/4885BTN3A1 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.