Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.37 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113921 | 0.81 | POLB (0.41) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL12436754 | 0.78 | CYP2C9 (0.40) | MAPTALDH1A1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL13950430 | 0.74 | MAPT (0.41) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL12438111 | 0.73 | CYP1A2 (0.51) | MAPTALDH1A1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL12437037 | 0.72 | MAPT (0.42) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL4398676 | 0.72 | PPARA (0.51) | MAPTALDH1A1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL11539611 | 0.71 | SLC22A12 (0.48) | MAPTALDH1A1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL2737144 | 0.69 | SLC6A4 (0.45) | MAPTALDH1A1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL8941845 | 0.69 | ALDH1A1 (0.58) | MAPTALDH1A1NPSR1KCNK2KCNK10 | |
| SCHEMBL8005997 | 0.69 | KCNK2 (0.54) | MAPTALDH1A1NPSR1KCNK2KCNK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304316-B1 | PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS | DAIKIN IND LTD (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-7311890-B2 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7311890-B2 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2007-12-25 | — | — | US | disclosed |