Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.38 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945879 | 0.80 | MAPT (0.41) | CYP2C19KIF11HSD17B10KCNK2KCNK10 | |
| SCHEMBL12436742 | 0.78 | PDK1 (0.39) | CYP2C9CYP2C19HSD17B10KCNK2KCNK10 | |
| SCHEMBL12438111 | 0.73 | CYP1A2 (0.51) | CYP2C9CYP2C19NPC1HTTMAPT | |
| SCHEMBL8941845 | 0.72 | ALDH1A1 (0.58) | KIF11KCNK2KCNK10NPC1HTT | |
| SCHEMBL8005997 | 0.72 | KCNK2 (0.54) | KIF11KCNK2KCNK10HTTLMNA | |
| SCHEMBL23077098 | 0.69 | MIF (0.44) | CYP2C9CYP2C19KIF11NPC1LMNA | |
| SCHEMBL4306807 | 0.69 | MAPT (0.36) | CYP2C9CYP2C19HSD17B10KCNK2KCNK10 | |
| SCHEMBL13950430 | 0.69 | MAPT (0.41) | CYP2C9CYP2C19HSD17B10KCNK2KCNK10 | |
| SCHEMBL4052304 | 0.69 | MAPT (0.54) | CYP2C9CYP2C19HSD17B10NPC1HTT | |
| SCHEMBL8941503 | 0.69 | LMNA (0.38) | CYP2C9CYP2C19HSD17B10KCNK2KCNK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304316-B1 | PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS | DAIKIN IND LTD (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-7311890-B2 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7311890-B2 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2007-12-25 | — | — | US | disclosed |