Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 3/20 | 0.54 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919991 | 0.90 | LMNA (0.53) | KCNK2KCNK10MAPK1SRD5A2MAPT | |
| SCHEMBL8941845 | 0.84 | ALDH1A1 (0.58) | KCNK2KCNK10MAPTLMNAHTT | |
| SCHEMBL15006775 | 0.83 | SRD5A2 (0.53) | MAPK1SRD5A2TSHRHTTHPGD | |
| SCHEMBL11106674 | 0.83 | KCNK2 (0.51) | KCNK2KCNK10MAPK1MAPTTSHR | |
| SCHEMBL282471 | 0.79 | TRPV1 (0.49) | KCNK2KCNK10MAPK1MAPTTSHR | |
| SCHEMBL8967091 | 0.78 | SRD5A2 (0.61) | MAPK1SRD5A2MAPTTSHRLMNA | |
| SCHEMBL9475945 | 0.78 | SRD5A2 (0.61) | MAPK1SRD5A2MAPTTSHRLMNA | |
| SCHEMBL9065412 | 0.77 | SRD5A2 (0.80) | MAPK1SRD5A2MAPTTSHRLMNA | |
| SCHEMBL10697158 | 0.77 | SRD5A2 (0.80) | MAPK1SRD5A2MAPTTSHRLMNA | |
| SCHEMBL51827 | 0.77 | SRD5A2 (0.80) | MAPK1SRD5A2MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077866-A | EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |