Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK1 | P53355 | 3/20 | 0.66 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404491 | 0.88 | DAPK1 (0.72) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL17115735 | 0.80 | DAPK1 (1.00) | DAPK1GALR3NR2F2HPGDSLC29A1 | |
| SCHEMBL12513072 | 0.80 | FLT4 (0.51) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL12436866 | 0.78 | DAPK1 (0.55) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL1404487 | 0.76 | DAPK1 (0.58) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL24709730 | 0.75 | EGFR (0.65) | DAPK1KDRHPGDEGFRALDH1A1 | |
| SCHEMBL3491211 | 0.75 | DAPK1 (0.57) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL6694591 | 0.75 | EGFR (0.60) | KDREGFRALDH1A1 | |
| SCHEMBL1404474 | 0.74 | DAPK1 (0.47) | DAPK1FLT4KDRGALR3NR2F2 | |
| SCHEMBL6690200 | 0.73 | TDP1 (0.49) | HPGDPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10036066-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2018-07-31 | — | — | US | disclosed |
| US-10036066-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2018-07-31 | — | — | US | disclosed |
| US-9598720-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2017-03-21 | — | — | US | disclosed |
| US-9598720-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2017-03-21 | — | — | US | disclosed |
| US-20160273035-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK A/S (DK) | 2016-09-22 | — | — | US | disclosed |
| US-9340824-B2 | Immunohistochemistry detection method | DAKO DENMARK A/S (DK) | 2016-05-17 | — | — | US | disclosed |
| US-9017992-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2015-04-28 | — | — | US | disclosed |
| US-20140315204-A1 | Immunohistochemistry Detection Method | DAKO DENMARK A/S (DK) | 2014-10-23 | — | — | US | disclosed |
| US-8741566-B2 | Immunohistochemistry and in situ hybridization detection method | DAKO DENMARK A/S (DK) | 2014-06-03 | — | — | US | disclosed |
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | DAKO DENMARK A/S (DK) | 2014-03-20 | — | — | US | disclosed |
| US-8546309-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2013-10-01 | — | — | US | disclosed |
| US-8481697-B2 | Nucleic acid base pairs | DAKO DENMARK A/S (DK) | 2013-07-09 | — | — | US | disclosed |
| US-20110177500-A1 | IMMUNOHISTOCHEMISTRY DETECTION METHOD | DAKO DENMARK AS (DK) | 2011-07-21 | — | — | US | disclosed |
| US-20100221705-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK APS (DK) | 2010-09-02 | — | — | US | disclosed |
| US-20100151460-A1 | Systems and Methods for Biological and Chemical Detection, Comprising Automatic Selection of Reagent Sets | DAKO DENMARK A/S (DK) | 2010-06-17 | — | — | US | disclosed |
| US-20100120054-A1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK APS (DK) | 2010-05-13 | — | — | US | disclosed |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
| US-20100105145-A1 | METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | PCNA, DCLRE1A, TK1 | DAPK1 2106/4885FLT4 199/4885KDR 398/4885 |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | NSUN3, NCL, NSUN2 | DAPK1 3183/4885FLT4 4574/4885KDR 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.