Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 9/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2321691 | 0.98 | CYP2A6 (0.50) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL25462183 | 0.81 | ALOX5 (0.51) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL2326181 | 0.80 | ALOX5 (0.46) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL14262914 | 0.80 | ALOX5 (0.51) | CYP2A6ALOX5HTR1AHTR1DSLC6A2 | |
| SCHEMBL6610537 | 0.80 | MAPT (0.46) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL6310788 | 0.77 | SLC6A2 (0.60) | ALOX5HTR1AHTR7HTR1DSLC6A2 | |
| SCHEMBL2967148 | 0.77 | ALOX5 (0.55) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL1095514 | 0.77 | ALOX5 (0.55) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| SCHEMBL2326178 | 0.77 | CA2 (0.56) | CYP2A6ALOX5HTR1AHTR7HTR1D | |
| Hydrochloric Acid SCHEMBL14775073 | 0.76 | SLC6A2 (0.59) | ALOX5HTR1AHTR7HTR1DSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535597-B2 | Photoreactive ligands and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-27 | — | — | US | disclosed |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2020-03-05 | — | — | US | disclosed |
| US-20120302546-A1 | NOVEL SULFAMIDES EXHIBITING NEUROPROTECTIVE ACTION AND METHODS FOR USE THEREOF | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302546-A1 | NOVEL SULFAMIDES EXHIBITING NEUROPROTECTIVE ACTION AND METHODS FOR USE THEREOF | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| WO-2011097337-A1 | NOVEL SULFAMIDES EXHIBITING NEUROPROTECTIVE ACTION AND METHODS FOR USE THEREOF | ADVANCED NEURAL DYNAMICS, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535597-B2 | Photoreactive ligands and uses thereof | CLTB, CRYAB, CRYAA | CYP2A6 3402/4885ALOX5 3452/4885HTR1A 2642/4885 |
| US-20120302546-A1 | NOVEL SULFAMIDES EXHIBITING NEUROPROTECTIVE ACTION AND METHODS FOR USE THEREOF | GRIK2, GRIK5, GRIN2A | CYP2A6 2362/4885ALOX5 273/4885HTR1A 1491/4885 |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | CLTB, CRYAB, CRYAA | CYP2A6 3402/4885ALOX5 3452/4885HTR1A 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.