Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CFB | P00751 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23664110 | 0.78 | HTT (0.70) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL15108922 | 0.78 | SMN1; SMN2 (0.59) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL13154979 | 0.78 | HTT (0.47) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL15746231 | 0.78 | HTT (0.47) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL12231810 | 0.78 | NOS3 (0.44) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL12232009 | 0.74 | HSD17B10 (0.38) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL13122856 | 0.74 | HTT (0.44) | HTTHSD17B10BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL12231816 | 0.72 | ALDH1A1 (0.54) | HTTHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18400252 | 0.71 | RIPK1 (0.37) | HTTHSD17B10BRAF | |
| SCHEMBL14336558 | 0.69 | METAP2 (0.44) | HTTHSD17B10ALDH1A1SMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, HCCS, NSUN2 | HTT 4314/4885HSD17B10 1474/4885BRAF 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.