Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513623 | 0.78 | ADORA2A (0.46) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL2521152 | 0.73 | LTA4H (0.58) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL207642 | 0.70 | HAO1 (0.53) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL8751962 | 0.68 | XDH (0.35) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7620872 | 0.67 | MEN1 (0.48) | ALDH1A1CYP1A2MAPK1NPC1RAB9A | |
| SCHEMBL11793141 | 0.67 | LTA4H (0.37) | ALDH1A1LTA4HTSHRKMT2AMAPT | |
| SCHEMBL16511926 | 0.66 | F2 (0.48) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL16511924 | 0.66 | MAP4K4 (0.54) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL4272018 | 0.65 | HAO1 (0.44) | HAO1HTTALDH1A1LTA4HTSHR | |
| SCHEMBL4268518 | 0.65 | LTA4H (0.60) | HAO1HTTALDH1A1LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709737-B2 | Bitter taste receptors | Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2014-04-29 | — | — | US | disclosed |
| US-8709737-B2 | Bitter taste receptors | Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20110177085-A1 | Bitter Taste Receptors | DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG, STIFTUNG DES OEFFENTLICHEN RECHTS, VERTRETEN DURCH DEN STIFTUNGSVORSTAND (DE) | 2011-07-21 | — | — | US | disclosed |
| US-20110177085-A1 | Bitter Taste Receptors | DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG, STIFTUNG DES OEFFENTLICHEN RECHTS, VERTRETEN DURCH DEN STIFTUNGSVORSTAND (DE) | 2011-07-21 | — | — | US | disclosed |
| US-7955808-B2 | Bitter taste receptors | Deutsches Institut für Ernährungsorschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2011-06-07 | — | — | US | disclosed |
| US-7955808-B2 | Bitter taste receptors | Deutsches Institut für Ernährungsorschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2011-06-07 | — | — | US | disclosed |
| US-20080287364-A1 | Bitter Taste Receptors | BUFE BERND | 2008-11-20 | — | — | US | disclosed |
| US-20080287364-A1 | Bitter Taste Receptors | BUFE BERND | 2008-11-20 | — | — | US | disclosed |
| US-7413867-B2 | Method for the identification of antagonists of a phenylthiocarbamide/bitter taste receptor | Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2008-08-19 | — | — | US | disclosed |
| US-7413867-B2 | Method for the identification of antagonists of a phenylthiocarbamide/bitter taste receptor | Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand (DE) | 2008-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287364-A1 | Bitter Taste Receptors | TAS2R30, TAS2R50, TAS2R10 | HAO1 3470/4885HTT 2401/4885ALDH1A1 2508/4885 |
| US-20110177085-A1 | Bitter Taste Receptors | TAS2R30, TAS2R50, TAS2R10 | HAO1 3470/4885HTT 2401/4885ALDH1A1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.