Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.50 |
| ▸ | NOS1 | P29475 | 7/20 | 0.50 |
| ▸ | NOS3 | P29474 | 5/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12262870 | 1.00 | NOS2 (0.50) | NOS2NOS1NOS3SLC7A5ARG1 | |
| SCHEMBL13287266 | 0.91 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5GRIK1 | |
| SCHEMBL16659160 | 0.91 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5GRIK1 | |
| SCHEMBL8101166 | 0.91 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5GRIK1 | |
| SCHEMBL14227023 | 0.91 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5GRIK1 | |
| Cystine SCHEMBL22491239 | 0.88 | NOS2 (0.52) | NOS2NOS1NOS3SLC7A5ARG1 | |
| Cystine SCHEMBL28772499 | 0.88 | NOS2 (0.56) | NOS2NOS1NOS3SLC7A5ARG1 | |
| Cystine SCHEMBL2400313 | 0.88 | NOS2 (0.52) | NOS2NOS1NOS3SLC7A5ARG1 | |
| Cystine SCHEMBL10225 | 0.88 | PTGS1 (0.50) | NOS2NOS1NOS3SLC7A5ARG1 | |
| Cystine SCHEMBL10224 | 0.88 | PTGS1 (0.50) | NOS2NOS1NOS3SLC7A5ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676818-B2 | Toll-like receptor 2-agonistic lipopeptides, and method of making the same | UNIVERSITY OF KANSAS (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | UNIVERSITY OF KANSAS | 2015-11-26 | — | — | US | disclosed |
| US-9040261-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | GLS, PKD1, CLIC1 | NOS2 1392/4885NOS1 587/4885NOS3 1421/4885 |
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | TLR2, TLR3, TLR1 | NOS2 3263/4885NOS1 4169/4885NOS3 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.