Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 9/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 9/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219360 | 0.77 | PIM1 (0.60) | ALDH1A1GLAL3MBTL1PIM1PIM3 | |
| SCHEMBL2220413 | 0.76 | PIM1 (0.55) | ALDH1A1GLAL3MBTL1PIM1PIM3 | |
| SCHEMBL1852290 | 0.76 | TNKS (0.63) | ALDH1A1GLAL3MBTL1PIM1PIM3 | |
| SCHEMBL20667972 | 0.73 | ALDH1A1 (1.00) | ALDH1A1GLAL3MBTL1PIM1PIM3 | |
| SCHEMBL15304529 | 0.71 | ALDH1A1 (0.68) | ALDH1A1GLAL3MBTL1PIM1PIM3 | |
| SCHEMBL1854681 | 0.69 | CSNK2B (0.73) | PIM1PIM3CSNK2A2CSNK2BPIM2 | |
| SCHEMBL13787063 | 0.69 | CSNK2A2 (0.45) | PIM1PIM3CSNK2A2CSNK2BPIM2 | |
| SCHEMBL1851596 | 0.69 | CSNK2B (0.61) | PIM1PIM3CSNK2A2CSNK2BPIM2 | |
| SCHEMBL1852847 | 0.69 | CSNK2B (0.58) | PIM1PIM3CSNK2A2CSNK2BPIM2 | |
| SCHEMBL4273392 | 0.69 | ALDH1A1 (0.63) | ALDH1A1GLAL3MBTL1PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178107-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178107-A1 | HCV PROTEASE INHIBITORS | HAVCR2, RNASE1, SERPINB1 | ALDH1A1 714/4885GLA 2042/4885L3MBTL1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.