SCHEMBL1243946

SCHEMBL1243946

Nc1cc(C(F)C(F)(F)C(F)(F)F)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
GAA P10253 7/20 0.52
ALOX12 P18054 3/20 0.52
HTT P42858 2/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 5/20 0.46
HPGD P15428 5/20 0.46
ALOX15 P16050 4/20 0.46
PKM P14618 2/20 0.46
USP2 O75604 2/20 0.46
MAPT P10636 6/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
RECQL P46063 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.35
HSP90AA1 P07900 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1871507 0.98 ALDH1A1 (0.50) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL3789315 0.86 ALOX15 (0.41) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL4424759 0.83 ALDH1A1 (0.36) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL29180096 0.82 ALDH1A1 (0.39) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL28454386 0.80 SHBG (0.45) HSD17B10KDM4ELMNAESR1ESR2
SCHEMBL14721886 0.79
SCHEMBL18037696 0.79 TDP1 (0.41) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL28454384 0.79 ESR1 (0.41) ALDH1A1ALOX12HIF1AHSD17B10HPGD
SCHEMBL28445609 0.79 HSD17B10 (0.41) ALOX12HIF1AHSD17B10HPGDALOX15
SCHEMBL3156196 0.79 TDP1 (0.41) ALDH1A1GAAALOX12HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116694005-B High-temperature-resistant perfluoroether rubber composition and preparation method and application thereof 上海芯密科技有限公司 2024-07-16 CN claimed
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN claimed
CN-118325281-A Flame-retardant high polymer material for aerospace equipment and preparation method thereof 东莞市卡帝德塑化科技有限公司 2024-07-12 CN claimed
CN-118325083-A Photosensitive polyamic acid ester resin, photosensitive polyamic acid ester resin glue solution, preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-07-12 CN claimed
CN-118335989-A Positive electrode binder composition and positive electrode 深圳好电科技有限公司 2024-07-12 CN claimed
CN-117902610-B Method for recycling sodium sulfate high-salt wastewater 天津大学 2024-07-05 CN claimed
CN-114561100-B Transparent polyimide solution, preparation method thereof, transparent polyimide film and application thereof 臻鼎科技股份有限公司 2024-07-05 CN claimed
CN-112180685-B Positive photosensitive resin composition, cured film and pattern processing method of cured film 武汉柔显科技股份有限公司 2024-06-25 CN claimed
CN-117866000-B Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-06-21 CN claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
EP-3315806-A1 BEARING MATERIAL, BEARING AND METHOD MAHLE Engine Systems UK Limited (GB) 2018-05-02 EP claimed
CN-103917916-A Polyimide light-sensitive resin composition for oled DONGJIN SEMICHEM CO LTD 2014-07-09 CN claimed
WO-2012166153-A1 THERMALLY REARRANGED (TR) POLYMERS AS MEMBRANES FOR ETHANOL DEHYDRATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (US) 2012-12-06 WO claimed
EP-1469037-B1 SOLVENT-SOLUBLE BLOCK COPOLYIMIDE COMPOSITION AND PROCESS FOR PRODUCING THE SAME PI R & D CO LTD (JP) 2008-08-06 EP claimed
CN-1301282-C Polyimide comprising sulfonic acid group at the terminal of side chain, and polymer electrolyte and fuel cell using the same SAMSUNG SDI CO LTD (KR) 2007-02-21 CN claimed
US-7022809-B2 Polyimides for anchoring liquid crystals, display devices including same and method for the preparation of said devices NEMOPTIC (FR) 2006-04-04 US claimed
CN-1660922-A Polyimide comprising sulfonic acid group at the terminal of side chain, and polymer electrolyte and fuel cell using the same SAMSUNG SDI ELECTRONICS CO LTD (KR) 2005-08-31 CN claimed
US-20040161541-A1 Polyimides for anchoring liquid crystals, display devices including same and method for the preparation of said devices NEMOPTIC (FR) 2004-08-19 US claimed
EP-1390807-A1 POLYIMIDES FOR ANCHORING LIQUID CRYSTALS, DISPLAY DEVICES INCLUDING SAME AND METHOD FOR THE PREPARATION OF SAID DEVICES Nemoptic (FR) 2004-02-25 EP claimed
WO-2002097524-A1 POLYIMIDES FOR ANCHORING LIQUID CRYSTALS, DISPLAY DEVICES INCLUDING SAME AND METHOD FOR THE PREPARATION OF SAID DEVICES NEMOPTIC (FR) 2002-12-05 WO claimed