SCHEMBL3156196

SCHEMBL3156196

Cc1ccc(C(F)C(F)(F)C(F)(F)F)cc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CASP1 P29466 1/20 0.41
CYP3A4 P08684 3/20 0.38
MAPT P10636 2/20 0.35
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
HTT P42858 1/20 0.32
HIF1A Q16665 1/20 0.32
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30
RAB9A P51151 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
PDE2A O00408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18037696 1.00 TDP1 (0.41) TDP1ALDH1A1CASP1CYP3A4MAPT
SCHEMBL6666750 0.86 CYP3A4 (0.41) TDP1ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL4424759 0.83 ALDH1A1 (0.36) TDP1ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL4004119 0.83 LMNA (0.32) ALDH1A1
SCHEMBL1243946 0.79 ALDH1A1 (0.52) TDP1ALDH1A1CYP3A4MAPTSMN1; SMN2
SCHEMBL7784834 0.79
SCHEMBL14721886 0.79
Hydrochloric Acid SCHEMBL1871507 0.77 ALDH1A1 (0.50) TDP1ALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL11804318 0.77 ALDH1A1 (0.50) TDP1ALDH1A1CASP1CYP3A4MAPT
SCHEMBL28213293 0.76 AOC1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490541-A Optical film having improved optical properties, display device including the same, and method of manufacturing the same 可隆工业株式会社 2023-07-25 CN claimed
CN-113072702-B Colorless transparent copolymerized polyimide film and preparation method thereof 上海大学(浙江·嘉兴)新兴产业研究院 2023-03-10 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN claimed
CN-113795536-A Polyamic acid composition and preparation method thereof, preparation method of polyimide film and polyimide film prepared from same (株) 大林公司 2021-12-14 CN claimed
CN-113439101-A Method for preparing polyamic acid composition containing novel dicarbonyl compound, polyamic acid composition, method for preparing polyamideimide film using the same, and polyamideimide film prepared by the same (株) 大林公司 2021-09-24 CN claimed
CN-111819732-B Protection member and wireless communication device 竹本直文 2021-09-10 CN claimed
CN-113243050-A Display substrate 昌盛SHEET股份有限公司 2021-08-10 CN claimed
CN-112831182-A Colorless transparent polyimide film, preparation method thereof and LED (light-emitting diode) film pasting screen 宁波长阳科技股份有限公司 2021-05-25 CN claimed
CN-108598533-B Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof 同济大学 2020-11-03 CN claimed
CN-111819732-A Protection member and wireless communication device 竹本直文 2020-10-23 CN claimed
CN-111386299-A Low color polymers for use in electronic devices E.I.内穆尔杜邦公司 2020-07-07 CN claimed
CN-110892003-A Low color polymers for flexible substrates in electronic devices 杜邦电子公司 2020-03-17 CN claimed
US-10550887-B2 Bearing material, bearing and method MAHLE ENGINE SYSTEMS UK LTD (GB) 2020-02-04 US claimed
WO-2019172348-A1 PROTECTIVE MATERIAL AND WIRELESS COMMUNICATION DEVICE 竹本 直文 2019-09-12 WO claimed
US-20180119740-A1 BEARING MATERIAL, BEARING AND METHOD MAHLE ENGINE SYSTEMS UK LTD (GB) 2018-05-03 US claimed
EP-3315806-A1 BEARING MATERIAL, BEARING AND METHOD MAHLE Engine Systems UK Limited (GB) 2018-05-02 EP claimed
EP-0385305-A1 Polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
US-4954610-A SOLVENT, HEAT, OXIDATION, AND CHEMICAL RESISTANCE HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
CN-107533259-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学工业株式会社 2024-06-21 CN disclosed
EP-1782881-A1 Membrane and associated method General Electric Company (US) 2007-05-09 EP disclosed