SCHEMBL1243947

SCHEMBL1243947

Nc1cc(C(F)(C(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.52
GAA P10253 7/20 0.52
MAPT P10636 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
PKM P14618 3/20 0.52
RECQL P46063 2/20 0.52
CHEK1 O14757 1/20 0.40
FYN P06241 1/20 0.40
PDGFRB P09619 1/20 0.40
PIM1 P11309 1/20 0.40
FGFR1 P11362 1/20 0.40
FLT1 P17948 1/20 0.40
GRK5 P34947 1/20 0.40
MAP2K2 P36507 1/20 0.40
MAPK8 P45983 1/20 0.40
CDK8 P49336 1/20 0.40
RPS6KA3 P51812 1/20 0.40
PRKX P51817 1/20 0.40
JAK3 P52333 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1871508 0.98 ALDH1A1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL16338898 0.87 ALDH1A1 (0.41) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL8809021 0.86 HSD17B10 (0.41) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL4424761 0.83 ALDH1A1 (0.36) ALDH1A1GAAMAPTMEN1KMT2A
4-Phenoxyaniline SCHEMBL2593558 0.83 MAOA (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL23174685 0.80 ESR1 (0.52) TDP1ESR1ARESR2
SCHEMBL28454387 0.80 HSD17B1 (0.35) ALDH1A1MEN1KMT2AHSD17B10ALOX15
SCHEMBL14721887 0.79 ALDH1A1 (0.35) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL1244478 0.79 ALDH1A1 (0.52) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL23174684 0.79 ALOX15 (0.46) ALDH1A1MEN1KMT2ARECQLALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN claimed
CN-116694005-B High-temperature-resistant perfluoroether rubber composition and preparation method and application thereof 上海芯密科技有限公司 2024-07-16 CN claimed
CN-118325281-A Flame-retardant high polymer material for aerospace equipment and preparation method thereof 东莞市卡帝德塑化科技有限公司 2024-07-12 CN claimed
CN-118325083-A Photosensitive polyamic acid ester resin, photosensitive polyamic acid ester resin glue solution, preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-07-12 CN claimed
CN-118335989-A Positive electrode binder composition and positive electrode 深圳好电科技有限公司 2024-07-12 CN claimed
CN-114561100-B Transparent polyimide solution, preparation method thereof, transparent polyimide film and application thereof 臻鼎科技股份有限公司 2024-07-05 CN claimed
CN-117902610-B Method for recycling sodium sulfate high-salt wastewater 天津大学 2024-07-05 CN claimed
CN-112180685-B Positive photosensitive resin composition, cured film and pattern processing method of cured film 武汉柔显科技股份有限公司 2024-06-25 CN claimed
CN-117866000-B Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-06-21 CN claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
CN-107579270-B Multi-branched polyaryletherketone anion exchange membrane and preparation method thereof 大连理工大学 2020-01-24 CN claimed
CN-110628372-A Flame-retardant adhesive 厦门宏晨电子产品有限公司 2019-12-31 CN claimed
CN-110591293-A Carbon fiber cable core pultrusion resin and preparation method thereof 东华大学 2019-12-20 CN claimed
US-20180119740-A1 BEARING MATERIAL, BEARING AND METHOD MAHLE ENGINE SYSTEMS UK LTD (GB) 2018-05-03 US claimed
EP-3315806-A1 BEARING MATERIAL, BEARING AND METHOD MAHLE Engine Systems UK Limited (GB) 2018-05-02 EP claimed
CN-103917916-A Polyimide light-sensitive resin composition for oled DONGJIN SEMICHEM CO LTD 2014-07-09 CN claimed
WO-2012166153-A1 THERMALLY REARRANGED (TR) POLYMERS AS MEMBRANES FOR ETHANOL DEHYDRATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (US) 2012-12-06 WO claimed
EP-1469037-B1 SOLVENT-SOLUBLE BLOCK COPOLYIMIDE COMPOSITION AND PROCESS FOR PRODUCING THE SAME PI R & D CO LTD (JP) 2008-08-06 EP claimed
CN-1301282-C Polyimide comprising sulfonic acid group at the terminal of side chain, and polymer electrolyte and fuel cell using the same SAMSUNG SDI CO LTD (KR) 2007-02-21 CN claimed
CN-1660922-A Polyimide comprising sulfonic acid group at the terminal of side chain, and polymer electrolyte and fuel cell using the same SAMSUNG SDI ELECTRONICS CO LTD (KR) 2005-08-31 CN claimed