Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422861 | 0.87 | MRGPRX4 (0.43) | SLC9A1HTR2APTGDR2MRGPRX4 | |
| SCHEMBL30995068 | 0.78 | HTR2A (0.44) | SLC9A1HTR2APTGDR2 | |
| SCHEMBL26487993 | 0.78 | MAP2K1 (0.41) | — | |
| SCHEMBL25085869 | 0.75 | HTR2A (0.44) | SLC9A1HTR2APTGDR2MRGPRX4 | |
| SCHEMBL12439663 | 0.74 | SLC6A9 (0.46) | — | |
| SCHEMBL421430 | 0.73 | — | — | |
| SCHEMBL10189611 | 0.73 | — | — | |
| SCHEMBL421721 | 0.72 | CA12 (0.52) | — | |
| SCHEMBL6908816 | 0.71 | IDO1 (0.38) | SLC9A1HTR2APTGDR2MRGPRX4 | |
| SCHEMBL423901 | 0.71 | GPR35 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095434-A1 | TETRAHYDRO-PYRAN DERIVATIVES AGAINST NEUROLOGICAL ILLNESSES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | WO | disclosed |