Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422975 | 0.86 | MRGPRX4 (0.41) | RBP4CES2PTGDR2MRGPRX4 | |
| SCHEMBL30628783 | 0.81 | CES2 (0.47) | CES2CACNA1H | |
| SCHEMBL6910600 | 0.75 | KIF11 (0.42) | CES2 | |
| SCHEMBL16449430 | 0.73 | PTGDR2 (0.46) | CES2PTGDR2 | |
| SCHEMBL16398462 | 0.73 | MRGPRX4 (0.41) | IDO1CES2PTGDR2MRGPRX4 | |
| SCHEMBL6909178 | 0.72 | CES2 (0.40) | CES2CACNA1H | |
| SCHEMBL16398013 | 0.72 | PTGDR2 (0.36) | IDO1CES2PTGDR2MRGPRX4 | |
| SCHEMBL422861 | 0.72 | MRGPRX4 (0.43) | PTGDR2SLC9A1MRGPRX4HTR2A | |
| SCHEMBL422141 | 0.71 | RBP4 (0.33) | IDO1RBP4CES2PTGDR2MRGPRX4 | |
| SCHEMBL12439665 | 0.71 | SLC9A1 (0.42) | PTGDR2SLC9A1MRGPRX4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023667-A1 | CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-03 | — | — | WO | disclosed |