SCHEMBL2324722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19791324	0.94	MAPK1 (0.39)	CYP11B2MAPK1MAPK13MAPK12MAPK11
	SCHEMBL2329554	0.93	MAPK1 (0.41)	CYP11B2MAPK1MAPK13MAPK12MAPK11
	SCHEMBL12440008	0.92	TLR7 (0.39)	CYP11B2MAPK1MAPK13MAPK12MAPK11
	SCHEMBL2321729	0.90	MAPK1 (0.42)	CYP11B2MAPK1FGFR1IKBKETBK1
	SCHEMBL12440239	0.90	MET (0.40)	CYP11B2MAPK1FGFR1TLR7KDR
	SCHEMBL12440010	0.89	MAPK1 (0.44)	CYP11B2MAPK1FGFR1IKBKETBK1
	SCHEMBL13968442	0.88	MAPK1 (0.41)	CYP11B2MAPK1FGFR1IKBKETBK1
	SCHEMBL12441196	0.88	MAPK1 (0.41)	CYP11B2MAPK1FGFR1IKBKETBK1
	SCHEMBL12439736	0.87	MAPK1 (0.41)	CYP11B2MAPK1FGFR1IKBKETBK1
	SCHEMBL13835189	0.86	NTRK1 (0.44)	MAPK1FEN1MAP4K4TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.