Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934839 | 1.00 | SCN9A (0.48) | SCN9ASCN10ABACE1TGFBR1USP2 | |
| SCHEMBL1935769 | 0.88 | MPL (0.42) | SCN9ASCN10AGAATDP1NPC1 | |
| SCHEMBL12439758 | 0.88 | MPL (0.42) | SCN9ASCN10AGAATDP1NPC1 | |
| SCHEMBL1935000 | 0.85 | TRPA1 (0.43) | SCN9ASCN10AALOX5APFEN1GAA | |
| SCHEMBL12439786 | 0.85 | TRPA1 (0.43) | SCN9ASCN10AALOX5APFEN1GAA | |
| SCHEMBL1935777 | 0.85 | SCN9A (0.44) | SCN9ASCN10ACYP3A4CYP2D6GAA | |
| SCHEMBL12439797 | 0.85 | SCN9A (0.44) | SCN9ASCN10ACYP3A4CYP2D6GAA | |
| SCHEMBL1934577 | 0.84 | ALOX5AP (0.44) | SCN9ASCN10AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1935109 | 0.84 | SCN9A (0.49) | SCN9ASCN10AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12514481 | 0.84 | SCN9A (0.49) | SCN9ASCN10AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332936-B1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2332936-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | SCN9A 3140/4885SCN10A 3517/4885BACE1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.